2 PICS | 4 DIAGRAMS; 1. The care and feeding to tumors | Angiogenesis is the development of new blood vessels, a process triggered by tumors as they grow. Tumors cannot survive without constantly forming new blood vessels to supply nutrients and carry off wastes. The blood vessels also become the transportation system that allows the cancer to spread, or metastasize, to distant parts of the body. Researchers are experimenting with ways to cut off the process at many differnt points, to deprive tumors of the blood they need. | Initiation 2. Invasion & proliferation 3. Maturation 4. Metastasis 5. Starving tumors: Photos of human tumors grown in chicken embryos show the effects of an antibody developed at Scripps Institute to block growth of blood vessels. The bottom two tumors were treated with the antibody; the top two were grwon the same amount of time without treatment. (E-4) 6. New cancer approach: Researchers [Peter C. Brooks] and [David Cheresh] continue work in their lab at Scripps Research Institute to refine proteins they designed to thwart angiogenesis, the growth of new blood vessels to feed tumors. (E-4) [1,2,3,4. SOURCE: KRT,AMA Encyclopedia of Medicine Graphic | (C) 1995 | Neil Pinchin Design 5. Scripps Research Institute; Cell 6. Union-Tribune / JIM BAIRD]